N-acylmannosamine kinase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from rat liver and Salmonella typhimurium converts N-acetylmannosamine to N-acetyl-D-mannosamine 6-phosphate by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP). The enzyme also accepts N-acyl derivatives other than N-acetyl, which are part of biochemical pathways to sialic acids.
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:N-acyl-D-mannosamine 6-phosphotransferase. Other names in common use include acylmannosamine kinase (phosphorylating), acetylamidodeoxymannokinase, acetylmannosamine kinase, acylaminodeoxymannokinase, acylmannosamine kinase, N-acyl-D-mannosamine kinase, N-acetylmannosamine kinase, and ATP:N-acetylmannosamine 6-phosphotransferase.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
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