Gluconokinase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from yeast and Escherichia coli converts the hexose sugar, D-gluconic acid, to 6-phospho-D-gluconic acid by transferring a phosphate group from the cofactor, adenosine triphosphate (ATP), which is converted to adenosine diphosphate (ADP). The enzyme is also found in mammalian kidney and Pseudomonas fluorescens.
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:D-gluconate 6-phosphotransferase. Other names in common use include gluconokinase (phosphorylating), and gluconate kinase.
Structural studies As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes , , , , , and .
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