ADP-specific phosphofructokinase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Pyrococcus furiosus converts fructose 6-phosphate to fructose 1,6-bisphosphate by transferring a phosphate group from the cofactor, adenosine diphosphate (ADP), which is converted to adenosine monophosphate (AMP).
This enzyme is a transferase, specifically one transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ADP:D-fructose-6-phosphate 1-phosphotransferase. This enzyme is also called ADP-6-phosphofructokinase, ADP-dependent phosphofructokinase.
Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .
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