McCardle is a surname. Notable people with the surname include:
Carl McCardle (1904–1972), American journalist and public official, Assistant Secretary of State for Public Affairs (1953–1957) Eliza McCardle Johnson (1810–1876), wife of President Andrew Johnson Fred McCardle (born 1951), Canadian politician, member of the Legislative Assembly of Prince Edward Island (2003–2007) Peter McCardle (born 1955), New Zealand politician William H. McCardle (1815–1893), American writer and editor William Wilson McCardle (1844–1922), member of the New Zealand Legislative Council
See also Ex parte McCardle, United States Supreme Court case McArdle