Purefoy is a surname. Notable people with the surname include:
Edward Bagwell Purefoy (1868–1960), British army officer and lepidopterist James Purefoy (born 1964), English actor Robert Purefoy, also Robert Parfew (d. 1557), bishop of Hereford William Purefoy (c. 1580–1659), one of the regicides of Charles I of England George Purefoy-Jervoise (1770–1847), English politician
See also Wilfred Bagwell Purefoy (1862–1930), British breeder of racehorses Purifoy Purify