Ureidosuccinase

Ureidosuccinase () is an enzyme that catalyzes the chemical reaction

The enzyme characterised from Zymobacterium oroticum hydrolyses N-carbamoyl-L-aspartic acid to aspartic acid, with ammonia and carbon dioxide as byproducts. The reaction is part of the breakdown of orotic acid.

This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-carbamoyl-L-aspartate amidohydrolase.

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