Acetylspermidine deacetylase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from rat liver hydrolyses N(8)-acetylspermidine to spermidine and acetic acid. The spermidine derivative with the acetyl group at the other end of the molecule (N(1)-acetylspermidine) is not reactive.
This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N8-acetylspermidine amidohydrolase. Other names in common use include N8-monoacetylspermidine deacetylase, N8-acetylspermidine deacetylase, N-acetylspermidine deacetylase, N1-acetylspermidine amidohydrolase (incorrect), and 8-N-acetylspermidine amidohydrolase.
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