2-(acetamidomethylene)succinate hydrolase () is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Pseudomonas species hydrolyses 2-(acetamidomethylidene)succinic acid to succinic semialdehyde and acetic acid, with ammonia and carbon dioxide as byproducts. The reaction is part of the breakdown of vitamin B6.
This enzyme is a hydrolase, one acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is 2-(acetamidomethylene)succinate amidohydrolase (deaminating, decarboxylating). This enzyme is also called alpha-(N-acetylaminomethylene)succinic acid hydrolase.
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