PFR may refer to:

Science and technology Plug flow reactor model, a reactor simulation model Prototype Fast Reactor, a nuclear reactor at Dounreay PFR, Phosphate Flame Retardant, a type of Flame Retardant pFR, a form of the light-sensing pigment phytochrome found in plants pFR, polymeric Flame Retardant, a type of Flame Retardant Polynomial Freiman-Ruzsa, a conjecture in Mathematics

Other Presidential Fleet Review Partito Fascista Repubblicano, a former political party in Italy Persons and Family Relations, one of the subjects covered in Civil Law on the Philippine Bar Examinations PFFR, an alternative rock group PFR (band) (Pray for Rain), a Christian music group PFR, product feature request Pontefract Baghill railway station, England; National Rail station code PFR Pork fried rice, a Chinese dish Portable Font Resource Prism fusion range, a clinical eye test to assess motor fusion Pro Football Reference, a statistics database for professional American football Promoted from Reserves (badminton)