Tupua may refer to:
The five principal gods of Niuean mythology, Fao, Fakahoko, Huanaki, Lage-iki, Lagi-atea Tipua, a spirit in Maori mythology Tupua Tamasese, the title of a paramount chief of Samoa Tufuga Efi, also known as Tupua Tamasese Tupuola Tufuga Efi, former Prime Minister of Samoa Tupua (spider), a spider genus