PATCO may refer to:
Professional Air Traffic Controllers Organization (1968), a defunct American labor union famous for its failed 1981 strike Professional Air Traffic Controllers Organization (2003), an independent American labor union Professional Air Traffic Controllers Organization (AFSCME), an affiliate of the American Federation of State, County and Municipal Employees Port Authority Transit Corporation (PATCO), operator of the PATCO Speedline, a transit line between Philadelphia, Pennsylvania, and Camden County, New Jersey PATCO Speedline, a rapid transit system running between Philadelphia, Pennsylvania and Camden County, New Jersey