Simpang Empat or Simpang Ampat or Sempang Ampat (Malay or Indonesian for "Four Corners") may refer to:
Malaysia Simpang Empat, Kedah Simpang Ampat (Malacca) Simpang Ampat, Seberang Perai Simpang Empat (Semanggol), Perak Simpang Empat, Perak Simpang Empat, Perlis Simpang Empat (state constituency), represented in the Perlis State Legislative Assembly
Indonesia Simpang Ampek, West Sumatra (occasionally known as Simpang Empat) Simpang Empat, Karo Regency, North Sumatra