Zzyzx or Zyzzyx may refer to:
Places Zzyzx, California, a place in the U.S., and Zzyzx Road, a road leading to it
Arts and entertainment Zyzzyx Road, a 2006 film directed by John Penney Zzyzx (Zeromancer album), 2003 Zzyzx (Os Mutantes album), 2020 Zzyzx (film), a 2006 film directed by Richard Halpern "Zzyzx Rd." (song), a 2007 song by Stone Sour from Come What(ever) May Zzyzx, a fictional underground research facility in the TV series Kyle XY Zzyzx, a fictional prison for demons in the novel series Fablehaven by Brandon Mull
Other uses Zyzzyx, a genus of sand wasp
See also Xyzzy (disambiguation) "Zzyzx Scarecrow", a song by Stavesacre from the 1997 album Absolutes Zyzyxia, a species of tropical shrub Zyzz, the persona that was used by Australian bodybuilder Aziz Shavershian Zzyzzyxx, a 1982 arcade game Captain Zzyzx, a novel by Michael Petracca