In enzymology, a phosphoamidase () is an enzyme that catalyzes the chemical reaction
N-phosphocreatine + H2O creatine + phosphate
Thus, the two substrates of this enzyme are N-phosphocreatine and H2O, whereas its two products are creatine and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphorus-nitrogen bonds. The systematic name of this enzyme class is phosphamide hydrolase. This enzyme is also called creatine phosphatase.
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