Choline sulfotransferase () is an enzyme that catalyzes the chemical reaction
The reaction converts choline to choline sulfate by transferring a sulfate group from the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS) and giving adenosine 3',5'-bisphosphate as a byproduct. The product is an osmolyte accumulated under saline conditions in organisms including Limonium species.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:choline sulfotransferase. This enzyme is also called choline sulphokinase.
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