Derksen is a Dutch surname which means son of Derk/Dirk, and may refer to:
Dirk Jan Derksen (born 1972), Dutch footballer Geert-Jan Derksen (born 1975), Dutch rower Jan Derksen (1919–2011), Dutch cyclist Johan Derksen (born 1949), Dutch footballer and sports journalist (editor-in-chief of Voetbal International) Kristina Tesser Derksen, Canadian politician Piet Derksen (1913–1996), Dutch businessman and founder of Center Parcs Rick Derksen, (born 1964) Dutch linguist Rob Derksen (1960–2004), American professional baseball pitcher Robert-Jan Derksen (born 1974), Dutch golfer