Niculescu is a Romanian surname. Notable people with the surname include:

Bogdan Niculescu-Duvăz (1948–2019), politician and architect Cezar Niculescu (1927–1981), basketball player Claudiu Niculescu (born 1976), soccer player Dan Niculescu (1929–1999), basketball player Luca Niculescu (born 1971), journalist and diplomat Margareta Niculescu (1926–2018), artist, puppeteer, director, teacher, and theater director Monica Niculescu (born 1987), tennis player Nifon Niculescu (1858–1923), bishop Oana Niculescu-Mizil (born 1975), politician Paul Niculescu-Mizil (1923–2008), communist politician Radu Niculescu (born 1975), soccer player Ștefan Niculescu (1927–2008), composer

See also Nicolescu