Gachechiladze () is a Georgian surname. Notable people with the surname include:
Gia Gachechiladze (born 1966), Georgian pop singer, actor, and media personality Givi Gachechiladze (born 1938), Georgian composer and conductor Levan Gachechiladze (1964–2025), Georgian politician and businessman Mikheil Gachechiladze (born 1990), Georgian rugby union player Shalva Gachechiladze (born 1987), Georgian show jumping champion Tamara Gachechiladze (born 1983), Georgian singer, songwriter, and actress