Sandworm may refer to:
Fictional animals Sandworm (Dune), from Frank Herbert's 1965 science fiction novel Dune and its derivative works.
Living animals Arenicola marina (lugworm), called "sandworm" in the UK Alitta virens, formerly Nereis virens (king ragworm), called "sandworm" in the US Hookworm larvae which cause cutaneous larva migrans, called "sandworms" in the southern US Sipunculus nudus (peanut worm), called "sandworm" in China
Other Sandworm (hacker group), a hacker group within the GRU, a military intelligence agency of the Russian Federation Sandworm: A New Era of Cyberwar and the Hunt for the Kremlin's Most Dangerous Hackers, a 2019 book about the group by Andy Greenberg Sandworm (installation), an environmental art installation in the Wenduine Beach, Belgium