ETS2 is a gene that in humans is encoding the C-ETS2 protein. The protein encoded by this gene belongs to the ETS family of transcription factors. It has been found to play a key role in the development of inflammatory bowel disease.
Interactions
ETS2 has been shown to interact with:
C-jun, Cyclin-dependent kinase 10, ERG, myb, and ZMYND11.
Clinical significance
ETS2 has been linked to a variety of diseases, including Takayasu's arteritis, inflammatory bowel disease, primary sclerosing cholangitis, and ankylosing spondylitis, all associated with a region on chromosome 21 at 21q22.
References
Further reading
External links Drosophila pointed - The Interactive Fly