Tabersonine 16-hydroxylase () is an enzyme that catalyzes the chemical reaction

Tabersonine 16-hydroxylase is a cytochrome P450 protein containing heme, isolated from Catharanthus roseus. It requires a partner cytochrome P450 reductase for functional expression. This uses nicotinamide adenine dinucleotide phosphate. The systematic name of this enzyme class is tabersonine,NADPH:oxygen oxidoreductase (16-hydroxylating). Other names in common use include tabersonine-11-hydroxylase, and T11H. It participates in indole alkaloid biosynthesis leading to vindoline.

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