Crystal skull refers to a number of human-like skull carvings made of quartz crystal and their associated myth and research.

Crystal skull may also refer to:

The Crystal Skull (video game), a 1996 adventure game Crystal Skull (Stargate SG-1), an episode of the TV show Stargate SG-1 Indiana Jones and the Kingdom of the Crystal Skull, the fourth movie in the Indiana Jones franchise. "Crystal Skull", a single by Mastodon from the album Blood Mountain

See also Skull (disambiguation)