In enzymology, (S)-2-hydroxy-fatty-acid dehydrogenase () is an enzyme that catalyzes the chemical reaction.
The two substrates of this enzyme are (S)-2-hydroxystearic acid and oxidised nicotinamide adenine dinucleotide (NAD). Its products are 2-oxostearic acid, reduced NADH, and a proton.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is (S)-2-hydroxystearate:NAD oxidoreductase. Other names in common use include dehydrogenase, L-2-hydroxy fatty acid, L-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.
See also (R)-2-hydroxy-fatty-acid dehydrogenase which acts on the enantiomer of the hydroxy acid.
References