In enzymology, a 2-(S)-hydroxypropyl-CoM dehydrogenase () is an enzyme that catalyzes the chemical reaction
2-(S)-hydroxypropyl-CoM + NAD+ 2-oxopropyl-CoM + NADH + H+
Thus, the two substrates of this enzyme are 2-(S)-hydroxypropyl-CoM and NAD+, whereas its 3 products are 2-oxopropyl-CoM, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 2-[2-(S)-hydroxypropylthio]ethanesulfonate:NAD+ oxidoreductase. This enzyme is also called 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase.
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