In enzymology, a testosterone 17beta-dehydrogenase is an enzyme that catalyzes the interconversion of testosterone and androstenedione.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.
Names The systematic name of this enzyme class is 17beta-hydroxysteroid:NAD+ 17-oxidoreductase. Other names in common use include 17-ketoreductase and 17beta-HSD. This enzyme participates in androgen and estrogen metabolism.
Variants There are two variants of the enzyme, one that uses NADP+ as cofactor, and one that uses NAD+ instead.
NAD+
This variant of testosterone 17beta-dehydrogenase () uses the cofactor oxidised nicotinamide adenine dinucleotide.
NADP+
This variant of testosterone 17beta-dehydrogenase () uses the cofactor oxidised nicotinamide adenine dinucleotide phosphate.
See also Testosterone glucuronide
References
External links Testosterone Enhancement