In enzymology, a L-arabinitol 4-dehydrogenase () is an enzyme that catalyzes the chemical reaction

The two substrates are L-arabinitol and oxidised nicotinamide adenine dinucleotide (NAD+). The products are L-xylulose, reduced cofactor NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arabinitol:NAD+ 4-oxidoreductase (L-xylulose-forming). Other names in common use include pentitol-DPN dehydrogenase, and L-arabitol dehydrogenase. This enzyme participates in pentose and glucuronate interconversions.

See also D-arabinitol 4-dehydrogenase

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