OSD may refer to:

Science and medicine Ocean Science Discussions, the discussion and review section of the journal Ocean Science Optimal shape design, a part of the field of optimal control theory Oral sedation dentistry, the oral administration of sedatives to facilitate dental procedures Oral solid dose, a form of oral administration of medication Osgood–Schlatter disease, an inflammation of the growth plate at the tibial tuberosity which occurs mostly in teenage boys

Technology and computing Object storage device, computer data storage device that manages data as objects Online standards development, platform for the development of standards of the International Electrotechnical Commission On-screen display, a feature of visual devices like VCRs and DVD players that displays program, position, and setting data on a connected TV or computer display Open Source Definition, criteria used by the Open Source Initiative to determine whether or not a software license can be considered open source OpenSearch Description document, an XML file format that identifies and describes a search engine Operating System Deployment, a component of Microsoft's System Center Configuration Manager product Orthotropic steel deck, a roofing and bridging technique

Other uses Åre Östersund Airport, Sweden, IATA airport code Office of the Secretary of Defense, the principal staff of the United States Secretary of Defense Officer on Special Duty, a Bangladeshi, Indian, and Pakistani civil service officer Oklahoma School for the Deaf, a K-12 residential school for the deaf or hard-hearing students Olympia School District, a school district in Olympia, Washington One Shot Deal, a live album by Frank Zappa posthumously released in 2008 Oregon School for the Deaf Overseas Surveys Directorate, the United Kingdom's central survey and mapping organisation for British colonies and protectorates 1984–1991 Oxnard Elementary School District, a school district in Oxnard, California