Michael Hughes may refer to:

Sports Michael Hughes (basketball) (born 1998), American basketball player Michael Hughes (footballer) (born 1971), Northern Irish footballer Michael Hughes (kicker) (born 2002), American football player Mickey Hughes (1866–1931), American MLB baseball pitcher of the 1880s and 1890s Mickey Hughes (boxer) (born 1962), English boxer of the 1980s and 1990s Mike Hughes (American football) (born 1997), American football player Mike Hughes (footballer) (1940–2018), Welsh footballer Mike Hughes (rower) (born 1959), Canadian rower Mike Hughes (wrestler) (born 1974), Canadian wrestler

Other Michael Hughes (industrialist) (1752–1825), Welsh industrialist Michael Hughes (priest) (died 1680), Welsh Anglican priest Michael Hughes (serial killer), American serial killer Michael Hughes-Young, 1st Baron St Helens (1912–1980), British army officer and politician Michael Hughes, member of English folk group The Young'uns Michael Anthony Hughes (born 1988), missing person who was abducted in 1994 Mike Hughes (daredevil) (1956–2020), American daredevil, amateur rocketeer, and flat Earth proponent Mikey Hughes, contestant in Big Brother UK