major histocompatibility complex (human), class I, B82 Alleles B*8201 Structure (See HLA-B) Symbol(s) HLA-B Locus chr.6 6p21.31

HLA-B*82 (B*82) is an HLA-B allele-group. There is no current useful serotyping for HLA-B*82 gene products. B*8201 was first identified by sequence analysis and appears to be derived by gene conversion between B*5602 and another HLA class I allele., later B*8202 was identified in a caucasian and was suggested to be ancestral to B*8201, as product between gene conversion of B*5602 allele and B*4501 allele. B*82 is more common in East Africa, Kenya and Sudan, the frequency of B*8201 is found in the peoples to the west, sporadically in Central and West Africa, and B*8202 is found in Sudan and Saudi Arabia.

Serotype + B82 serotype recognition of Some HLA B*82 allele-group gene productsderived from IMGT/HLA B*82 B82 other Sample allele % % size (N) *8201 3 79 146

Allele frequencies + HLA B*8201 frequencies freq ref. Population (%) Luo (Kenya) 1.9 Guinea Bissau0.8 Natal Zulu (S. Africa) 0.5 Beti (Cameroon)0.3 Kenya 0.3 Kampala (Uganda) 0.3 Nandi (Kenya)0.2 ' HLA B*8202 frequencies Sudanese2.5 Kenya 0.7 Guraiat and Hail (Saudi Arabia)0.2

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