Guama can refer to:

People Guamá, a Taíno cacique who led a rebellion against the Spanish rule in Cuba in the 1530s

Places Guama, Brazil, a small town in the state of Pará in Brazil, Guamá, Cuba, a municipality in Santiago de Cuba Province, Cuba Guama, Venezuela, a town in Yaracuy state, Venezuela Guamá, San Germán, Puerto Rico, a barrio in the San Germán municipality of Puerto Rico (U.S.)

Plants Guama, Spanish name of Inga edulis (Ice-cream-bean) in South America.