Trifluoroacetate () is a polyatomic ion, the anion that is the conjugate base of trifluoroacetic acid (CF3CO2H).

Production The salts containing the trifluoroacetate anion can be made by an acid–base reaction between trifluoroacetic acid and a base, such as sodium hydroxide (NaOH) to give sodium trifluoroacetate (CF3COONa):

CF3CO2H + NaOH ⟶ CF3CO2Na + H2O

Trifluoroacetate as a PFAS Trifluoroacetic acid is one of the shortest possible perfluoroalkyl substances (PFAS). It is suspected to be a persistent pollutant.National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 84468, Trifluoroacetate. Retrieved October 11, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/Trifluoroacetate.

Related compounds Fluoral Trichloroacetic acid Acetate

References