CSCS may refer to:

Organisations Centro Svizzero di Calcolo Scientifico, the Swiss National Supercomputing Centre Chhattisgarh State Cricket Sangh, India Colorado Springs Christian Schools, Colorado, US Coral Springs Charter School, Florida, US

Other uses cscs, an allele pattern in cats that results in blue eye pigmentation

Certified Strength and Conditioning Specialist, a professional certification for strength and conditioning coaches Construction Skills Certification Scheme, United Kingdom recognized professional designation Cross-Strait CEO Summit, a business summit between Mainland China and Taiwan

See also CSC (disambiguation)