Sankt Margarethen or St. Margarethen may refer to the following places:
Sankt Margarethen, Germany, a municipality in Schleswig-Holstein in Austria: Sankt Margarethen an der Raab, in Styria Sankt Margarethen an der Sierning, in Lower Austria Sankt Margarethen bei Knittelfeld, in Styria Sankt Margarethen im Burgenland Sankt Margarethen im Lungau, in Salzburg St. Margarethen, a settlement in the municipality of Münchwilen, Thurgau, Switzerland
See also Saint Margaret Sankt Margareten im Rosental, a town in Carinthia, Austria St. Margrethen, a municipality in the canton of St. Gallen, Switzerland St. Margrethen railway station St. Margrethen–Lauterach line