(The) Last Man on Earth may refer to:

Last Man on Earth (book), science fiction anthology edited by Isaac Asimov Last Man on Earth (album), a 2001 album by Loudon Wainwright III "The Last Man on Earth" (song), a 2021 song by Wolf Alice from their album Blue Weekend The Last Man on Earth (1924 film), a silent comedy film The Last Man on Earth (1964 film), an Italian science fiction film starring Vincent Price The Last Man on Earth (2011 film), an Italian science fiction film by Gipi The Last Man on Earth (TV series), a 2015 American comedy television series

See also The Last Man on Planet Earth, a 1999 television movie Y: The Last Man, a science fiction comic book series Last Woman on Earth, 1960 science fiction film Last One on Earth, 1992 album The Last Man (disambiguation)