GPHS can mean:
Schools Australia: Glenmore Park High School, a co-educational, comprehensive government high school in Glenmore Park, New South Wales
Canada: Grant Park High School, in Winnipeg, Manitoba, Canada
The Philippines: Gregorio Perfecto High School, in Manila, Philippines
United States: Gage Park High School, in Chicago, Illinois Galena Park High School in Galena Park, Texas (Houston area) Gatlinburg-Pittman High School, in Gatlinburg, Tennessee Glacier Peak High School, in Snohomish, Washington Gwynn Park High School, in Brandywine CDP, Prince George's County, Maryland (Washington, DC area)
Other General Purpose Heat Source, a radioisotope source used in space power generation