HBB could refer to:
Science Hexabromobenzene Beta globin (HBB, β-globin or haemoglobin, beta) a globin protein in adult human hemoglobin A. Human β-globin locus
Places Headbangers Ball National Rail station code for Hubberts Bridge railway station, England
Television Has Bilgi Birikim - a defunct Turkish television channel. Hybrid Broadcast Broadband TV European initiative to combine broadcast television with the internet
Other Humongous Bank and Broker - Informal term used to denote very large financial institutions in the United States Honey Badger Brigade (or Twitter account HoneyBadgerBite), a website launched November 2013 based on the Honey Badger Radio series launched August 2013 on BlogTalkRadio on the AVoiceforMen channel. Home-based business, a type of small business