Gepefrine, also known as 3-hydroxyamphetamine or α-methyl-meta-tyramine and sold under the brand names Pressionorm and Wintonin, is a sympathomimetic medication used as an antihypotensive agent which has been marketed in Germany.
Pharmacology Gepefrine is described as a sympathomimetic and antihypotensive agent.
Chemistry Gepefrine, also known as 3-hydroxy-α-methylphenethylamine or as 3-hydroxyamphetamine, is a substituted phenethylamine and amphetamine derivative. It is used pharmaceutically as the (S)-enantiomer and as the tartrate salt. Related compounds include meta-tyramine (3-hydroxyphenethylamine), 4-hydroxyamphetamine (norpholedrine), 3,4-dihydroxyamphetamine (α-methyldopamine), and metaraminol ((1R,2S)-3,β-dihydroxyamphetamine), among others.
History Gepefrine was synthesized by 1968 and was introduced for medical use in Germany by 1981.
Society and culture Names Gepefrine is the generic name of the drug and its . Brand names of gepefrine include Pressionorm and Wintonin.
Other drugs Gepefrine is a known metabolite of amphetamine in rats.
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