The relaxin receptors are a subclass of four closely related G protein-coupled receptors (GPCR) that bind relaxin peptide hormones.
Below is list of human relaxin receptors, their endogenous peptide hormones, and what downstream enzymes are activated or inhibited by the receptor.
receptor/gene ligands activates inhibits relaxin 1, relaxin 2, relaxin 3 adenylate cyclase, protein kinase A, protein kinase C, phosphatidylinositol 3-kinase, extracellular signal-regulated kinases (Erk1/2) relaxin 1, relaxin 2, insulin-like 3 adenylate cyclase relaxin 3 Erk1/2 signaling adenylate cyclase relaxin 3, insulin-like 3 adenylate cyclase
See also Relaxin family peptide hormones Insulin/IGF/Relaxin family Relaxin/insulin-like family peptide receptor 1
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