The following highways are numbered 216:
Canada Alberta Highway 216 Manitoba Provincial Road 216 Prince Edward Island Route 216 Quebec Route 216 Nova Scotia Route 216
China China National Highway 216
Costa Rica National Route 216
India National Highway 216 (India)
United Kingdom road B216 road
United States U.S. Route 216 (former) Alabama State Route 216 California State Route 216 Connecticut Route 216 Florida State Road 216 (former) Georgia State Route 216 K-216 (Kansas highway) Kentucky Route 216 Maine State Route 216 Maryland Route 216 M-216 (Michigan highway) Minnesota State Highway 216 (former) Montana Secondary Highway 216 (former) New Mexico State Road 216 New York State Route 216 North Carolina Highway 216 Ohio State Route 216 Oregon Route 216 Pennsylvania Route 216 Rhode Island Route 216 South Carolina Highway 216 Tennessee State Route 216 Texas State Highway 216 (former) Texas State Highway Loop 216 (former) Texas State Highway Spur 216 Utah State Route 216 (former) Virginia State Route 216 Wyoming Highway 216