Up and Down, or variants, may refer to:

Up and down, relative vertical directions

Film Up and Down (1965 film), an Italian film Up and Down (2004 film), a Czech film Up & Down: Mukalil Oralundu, a 2013 Indian Malayalam-language film

Music Albums Up & Down (Horace Parlan album) or the title track, 1963 Up and Down (Opus album) or the title song, 1984 Up and Down (Liane Carroll album), 2011 Up & Down – The Party Album, by Vengaboys, or the title song (see below), 1998 Up and Down, an EP by She Wants Revenge, 2009

Songs "Up & Down" (Eddy Huntington song), 1987 "Up & Down" (EXID song), 2014 "Up and Down" (Vengaboys song), 1998 "Up & Down (In & Out)", by Deborah Cox, 2002 "Up n' Down", by Britney Spears from Femme Fatale, 2011 "Up and Down", by the Cars from Panorama, 1980 "Up and Down", by Doja Cat from Planet Her, 2021 "Up and Down", by Duane Eddy, 1958 "Up n Down", by Eunhyuk from Explorer, 2025 "Up and Down", by Eyes of Blue, 1966 "Up and Down", by the High, 1990 "Up and Down", by John Fred, 1967 "Up and Down", by the McCoys, 1966 "Up and Down", by Pet Shop Boys from the single "Did You See Me Coming?", 2009 "Up and Down", by Peter Combe from Songs for Little Kids, 1982 "Up and Down", by the Shoes, 1974 "Up and Down", from Sesame Street, 1970 "Up/Down", by Jessica Mauboy, 2008 "Up Down" (Morgan Wallen song), 2017 "Up Down (Do This All Day)", by T-Pain, 2013

Television "Up & Down", an episode of the TV series Pocoyo

Other uses Up and Down (Goya), a 1799 engraving by Francisco de Goya Up and down (rail directions) Up'n Down, a 1983 arcade game Up and down, a traveling violation in basketball

See also Ups and Downs (disambiguation)