Ndungane is a surname. Notable people with the surname include:

Akona Ndungane (born 1981), South African rugby union player Odwa Ndungane (born 1981), South African rugby union player, twin of Akona Njongonkulu Ndungane (born 1941), Archbishop of Cape Town Sbabalwe Ndungane (born 2002), South Africa rowing athlete at UFHRC