2,α-Dimethyltryptamine

2,α-Dimethyltryptamine (2,α-DMT), also known as 2-methyl-α-methyltryptamine (2-Me-αMT or 2-Me-AMT), is a tryptamine and a lesser-known psychedelic drug. It is the 2,α-dimethyl analogue of DMT and the 2-methyl derivative of α-methyltryptamine (αMT or AMT).

Use and effects In his book TiHKAL (Tryptamines I Have Known and Loved), Alexander Shulgin lists 2,α-DMT's dose as 300 to 500mg orally and its duration as 7 to 10hours. The effects of 2,α-DMT have been reported to include feeling intoxicated or drunk-like, feeling good and peaceful, things feeling softer and richer, brighter lights, flashes on edge of visual field, daydreaming with music, completely clear thinking, eating food being an adventure, facial tingling, impaired motor coordination, easy sleep, and next-day dehydration.

Chemistry Synthesis The chemical synthesis of 2,α-DMT has been described.

Analogues Analogues of 2,α-DMT (2-methyl-AMT) include 2-methyltryptamine (2-MT or 2-Me-T), 2,N,N-TMT (2-methyl-DMT), 2-methyl-DET, and 5-MeO-2-TMT (2-methyl-5-MeO-DMT), among others.

History The chemical synthesis of 2,α-DMT was first reported in 1965.

2,α-Dimethyltryptamine

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