José Ruiz may refer to:
Artists and entertainers José Ruiz y Blasco (1838–1913), Spanish painter, father of Pablo Picasso José Martínez Ruiz (1873–1967), Spanish writer and literary critic José Carlos Ruiz (born 1936), Mexican film actor
Crime Jose Ruiz (Chepe), American man accused in the 1942 death of José Gallardo Díaz
Politicians José Francisco Ruiz (1783–1840), Texas revolutionary and politician José Ruiz, Cuban plantation owner, defendant in the Amistad Case
Sportspeople José Ruiz (footballer, 1904–1962), Mexican football forward José Luis Ruiz (born 1952), Spanish long-distance runner José Ruíz Matos (1966–1992), Puerto Rican boxer José Oliver Ruiz (born 1974), Colombian weightlifter José Manuel Ruiz Reyes (born 1978), Spanish table tennis player José Ruiz (sailor) (born 1980), sailor José Hiber Ruiz (born 1980), Mexican football midfielder José Ruiz (futsal player) (born 1983), Spanish futsal player José Julio Ruiz (born 1985), Cuban baseball player José Ruiz (baseball) (born 1994), Venezuelan baseball player José Ruiz, French head coach of the Mali national basketball team