T45, T.45 or T-45 may refer to:
Vehicles Cooper T45, a racing car McDonnell Douglas T-45 Goshawk, an American trainer aircraft SJ T45, a Swedish diesel-electric locomotive Slingsby T.45 Swallow, a British glider Type 45 destroyer, a destroyer class of the Royal Navy T45 Roadtrain, a 1988 Leyland Motors tractor truck
Other uses T45 (classification), a disabled sports handicap class for arm amputees T.45 (standard), an ITU standard for run-length encoding