Methanoculleus is a genus of microbes within the family Methanomicrobiaceae. The species of the genus Methanoculleus live in marine environments brackish water, and are very common in bioreactors, landfills, and wastewater. Unlike other archaea, Methanoculleus and some species of related genera can use ethanol and some secondary alcohols as electron donors as they produce methane. This has implications as the production of methane as a greenhouse gas and consequences with respect to global climate change.

Phylogeny The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI).

16S rRNA based LTP_07_2026 53 marker proteins based GTDB 11-RS232 Species incertae sedis: "Ca. M. ammoniitolerans" Weng et al. 2024 "M. bovis" Trubitsyn et al. 2025

See also List of Archaea genera

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Further reading