Kühne is a surname. Notable people with the surname include:
Alfred Kühne (1895–1981), German businessman Alfred von Kühne (1853–1945), Prussian general Anke Kühne (born 1981), German field hockey player August Kühne (1855–1932), German businessman
Eric Kuhne (1951–2016), American-born British architect Frank Kühne (born 1961), German swimmer
Friedrich Kühne (1870–1959), German actor
Hans Kühne (1880–1969), German chemist and businessman Helmut Kuhne (born 1949), German politician
Klaus-Michael Kühne (1937-2026), German billionaire and businessman Louis Kuhne (1835–1901), German naturopath
Marc Kühne (born 1976), German bobsledder Matthias Kühne (born 1987), German footballer
Otto Kühne (1893–1955), German politician
Rita Kühne (born 1947), East German sprinter Roy Kühne (born 1967), German politician Simon Kühne (born 1994), Liechtenstein footballer Stefan Kühne (born 1980), German footballer and coach Thomas Kühne (born 1958), German historian
Walter Georg Kühne (1911–1991), German paleontologist
See also