Theaflavin digallate (TFDG) is an antioxidant natural phenol found in black tea, and a theaflavin derivative.
Health TFDG is a scavenger of superoxide in vitro, even more so than EGCG. Tea polyphenols including TFDG reduce angiogenesis, which is implicated in non-liquid cancers, an area of intense current research, by decreasing vascular endothelial growth factor production and receptor phosphorylation. TFDG inhibits activity of the enzyme 3CLpro in vitro.
References