HLA-DR6 (DR6) is a broad-antigen serotype that is further split into HLA-DR13 and HLA-DR14 antigen serotypes.
Serology + DR13, DR6 and other serotype recognition of some DRB1*13 and DRB1*14 allelesderived from IMGT/HLA DRB1* DR13 DR6 DR14 Sample allele % % % size (N) 1301 81 14 1 3788 1302 74 17 2 3081 1303 69 10 2 948DR12 - 3%, DR11 - 3% DR5-2% 1304 87 127 1305 54 12 305DR12 - 6%, DR11 - 7% DR5-4% 1306 78 9 1307 >50 1 1308 45 55 9 1310 >75 5 DRB1* DR14 DR6 DR13 N 1401 74 14 3 1942 1402 61 13 9 204 1403 72 12 2 37 1404 79 8 80DR1404 - 3% 1405 86 10 58 1406 37 15 22 117 1407 90 10 1408 25 4DR4 - 25% 1410 >75 4
DR6 serological reactivity is relatively poor compared to other serological tests for DR antigens. Compare to DQ2 or DR7.
Disease associations DR13 and DR14 share a common association to myasthenia gravis.
Allele groups HLA-DRB1*13 and HLA-DRB1*14 encode serotypes of DR6.
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