James Cooley (1926–2016) was an American mathematician.
James Cooley may also refer to:
James Cooley (diplomat), U.S. Ambassador to Peru (1826–1828) James E. Cooley (1802–1882), New York City bookseller, auctioneer and politician Mesita (musical project), by James Cooley See also James C. Field (James Cooley Field), American photographer James Cooley Fletcher (1823–1901), missionary