Margarita Island, or similar spellings, may refer to: Isla Margarita, the main island of Nueva Esparta state, Venezuela Margarita Island (Colombia), an island in the Magdalena River, Colombia Isla Santa Margarita, Magdalena Bay, Baja California Sur, Mexico Margaret Island, or Margitsziget, in Budapest, Hungary Margeret Island (Panama) Margarita Island (Panama)